It took me a while to figure how to properly generate citations for a manuscript for SPIE. The following is for Lyx 1.6.
Document class: “article (REVTeX 4)” Custom class options: “supercite, prb,nobibnotes” “supercite” causes superscripts to be used at the list of cited sources “prb” causes superscripts to be used for in-document citations “nobibnotes” […]